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2006;47(1):17483 Rossi M, Johnson DW, Morrison M, Pascoe E, Coombes JS, Forbes JM,

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Conclusion: The study underscores DSIP-CBBBP potential in correcting neurotransmitter dysregulation and promoting sleep, hinting at its utility in sleep-related therapies

Further studies are in progress to design clinically viable candidates through structure-based drug design approaches using the co-crystal structures of our lead inhibitors

It engages the same amylin/calcitonin receptors in the same hindbrain area postrema as native amylin and pramlintide, 5 11 and it drives the same vagally mediated slowing of the stomach that Samsom and colleagues quantified for pramlintide