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Moreover, the PINK1 activator ABBV-1088 (Mitokinin/AbbVie) and the USP30 inhibitor MTX325 (Mission Therapeutics) are both entering Phase 1 clinical trials as the first selective mitophagy enhancers to treat PD

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J Plant Physiol

The Western lifestyle with its ultra-processed foods, reliance on medications, and high exposure to chemicals or environmental pollutants seems to lay the foundation for the proliferation of free radicals