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Sirtuins are a family of 7 enzymes (SIRT1 to SIRT7) that use the NAD + as a co-substrate for their deacetylation activity

This depletion can further exacerbate the vulnerability of neurons to oxidative stress, contributing to the onset of depressive symptoms

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Song C, Vandewoude M, Stevens W, De Clerck L, Van der Planken M, Whelan A, et al

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