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The authors made different hypotheses to explain this data: 1) the lower iodine intake, frequently detected in vegetarians and vegans compared to other type of dietary pattern users, as well as 2) the possible role of the lower iron intake that characterizes subjects following a plant-based diet [177]

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The relationship between diabetes and cognitive impairment involves many aspects, including central insulin signal transduction, nerve fiber damage caused by hyperglycemia, neuritis, oxidative stress, bloodbrain barrier damage, vascular neuropathy, changes in the dopaminergic system, and the effects of advanced glycation end products on metabolism and energy (Figure 1)