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Open questions also include an unresolved debate in the peer-reviewed literature about the implications of BPC-157s pro-angiogenic activity for cancer-relevant signaling pathways, raised in a 2025 literature review and disputed by the original research group

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Scientific study has also addressed its stability properties across biological matrices, pharmacokinetic behavior in preclinical species, and interaction with the dopaminergic system in controlled neurological research models

[Google Scholar] 96.Niihara Y., Miller S.T., Kanter J., Lanzkron S., Smith W.R., Hsu L.L., Gordeuk V.R., Viswanathan K., Sarnaik S., Osunkwo I., et al

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