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Heterogeneity was low and non-significant when these were excluded

The magnitude of weight loss was dose-dependent, with the 2.4 mg dose showing a clinically meaningful reduction

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The EV strain grew slightly faster with a maximum growth rate of 0.52 h 1 and an average final OD 600 of 17.3, whereas the TML2Car strain grew at a rate of 0.46 h 1 to an average OD 600 of 15.3 at the end of the fermentation after 48 h, with all strains converting 50% of the provided carbon source glycerol

We provide detailed post-injection aftercare instructions that are just as important as pre-injection prep