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The inflammatory cellular infiltration, such as neutrophils and macrophages, mediating prolonged airway inflammation can be induced, and inflammatory cytokines are released, such as TNF- as an initial proinflammatory cytokine stimulating the expression of downstream cytokines, such as IL-1(6)

Glutathione and other thiols in biological samples can interfere with the assay

Others note temporary tiredness during the initial adjustment period