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High cortisol levels can also contribute to the development of conditions such as depression, anxiety, and sleep disorders.Insulin resistance can also affect the balance of sex hormones, such as estrogen and testosterone

55.9 years), sex (female, 73.1% in both), race (Black/African American, 76% vs

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Hence, it can be concluded that there is a 13-fold increase in the bioavailability of diosgenin due to presence of piperine