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(2004) reported comparable rates of tolerance development and completely symmetrical cross-tolerance during continuous i.c.v

In this regard, increased loss of glutathione may change the intracellular environment to a prooxidant state and thereby caused prominent changes in gene expression, which is ultimately evolving into a malignant state [26]

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With regular use, it reveals a smoother, brighter, and more radiant complexion

In the intracellular pathway, drugs are internalized by olfactory neurons through endocytosis, transported to the end of the axon, and subsequently released into the brain via exocytosis (Figure 2)