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2 Diuretics: brief historic perspectives 2.1 Thiazides and thiazide-like diuretics Hydrochlorothiazide and chlorthalidone, a benzothiadiazide and a thiazide-like diuretic, respectively were introduced during 1957-59 and the former quickly became a mainstay in the treatment of hypertension

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and (4) prioritizing research on chronic, low-dose, and mixture exposures

Owing to the poor biocompatibility and degradability of many nanomotor components, biological enzyme-driven motors represent a hybrid approach that enables both self-propulsion and biocatalysis [103]

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