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This was confirmed by the EPIC InterAct Case-Cohort Study which showed that obesity has a greater weight in defining the absolute risk of T2D than genetics [18]

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Indeed, the model values are all within 1% of the data for the relative change in body weight across placebo, 5, 10, and 15 mg doses of tirzepatide measured at 11 time points over the 72 week study

It raises crucial questions about the sustainability of treatment effects and the practical implications of potentially indefinite therapy