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Interestingly, SFN-GSH was the 3rd most abundant metabolite detected in this study (after phosphorylcholine and PC(34:1)) based on LC-MS peak height, while SFN adducts with other peptides and amino acids were detected a low levels (Fig 7A and B)
According to some scientists, hydrogen peroxide (H 2 O 2 ) also belongs to this group since it easily penetrates the membranes and in the presence of transition metals (copper or iron) it can be reduced to OH as in the example below (Yu, 1994): Hydroxyl radical is the strongest oxidant generated in biological systems because of its extremely short half-life (Yu, 1994
This decision was based on the results of controlled excretion studies as well as scientific literature indicating that only high doses of pseudoephedrine improved sports performance
conditions with HPA axis dysregulation (burnout, chronic stress, PTSD)
D.TostesK.et al (2021)
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