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The headline result was an average weight loss of 13.6% with oral semaglutide, compared with 2.2% with placebo

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Experts say these side-effects can relate to the way the medications work: slowing the progress of food through the digestive tract, slowing stomach emptying and affecting signalling from the gut to the brain

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Dulaglutide and insulin microsecretion in people with type 1 diabetes (DIAMOND-GLP-1): A randomized double-blind placebo-controlled trial