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Currently, research on the Neh3 domain and the C-terminal transcriptional activation domains (Neh4 and Neh5) is limited

The animal studies used both local application at the injury site and systemic administration (intraperitoneal and intragastric), with both routes showing significant effects

After being abundantly absorbed by the cells it inhibits tyrosinase production which reduces melanin synthesis

Furthermore, EGCG has inhibitory effects on the proliferation and invasion of lung cancer cells in vitro (Jin et al., 2015)

Siegenthaler PA, Packer L (1965) Light-dependent volume changes and reactions in chloroplasts