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Acknowledgements This work was supported by research grants from the National Key Research and Development Program of China (2016YFA0100501), the Chinese National 973 Program (2012CB517502), the National Natural Sciences Foundation of China (81400798, 81400767, 81401142, 81270858, and 81570692), and the Beijing Natural Sciences Foundation of China (7163233)

IGF-1 and its analogs have been central to studies examining cellular proliferation, communication, and signaling mechanisms

Ask your healthcare provider if youre on the right dose and if its been enough time