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Statistical charts related to the molecular simulation data were generated using OriginPro

Since glutathione plays such a pivotal role in the body, factors that may contribute to its depletionincluding certain lifestyle habits, environmental exposures, and pharmaceutical useare of increasing interest to researchers and health-conscious individuals alike

Therefore, GLS1 inhibitors (especially CB-839) have been described to restrain tumor cells proliferation, and also, due to a higher availability of interstitial glutamine, support the antitumor effects of CD8 + T cells, increasing their infiltration and reducing Tregs [203, 204]

The peptide was well-tolerated with minimal adverse effects

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