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10.1186/1471-2148-8-39 BMC Evol

CGRP, when released from the bodies or axonal swellings of stimulated trigeminal neurons, can trigger satellite glial cells within the trigeminal ganglia, as well as microglia and astrocytes in the trigeminal nucleus caudalis

This transcriptional activation provides sustained protection against oxidative stress by increasing cellular antioxidant enzyme capacity

amarum ) (Safitri et al., 2019)

64 This dynamic approach helps maintain a stable environment in which the newly differentiating chondrocytes are constantly receiving the necessary signals to build, remodel, and reinforce the ECM