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Cell viability assay Cell viability was assessed using the MTS assay (CellTiter 96 AQueous One Solution Cell Proliferation Assay, Promega) according to the manufacturers instructions
Acute Kidney Injury: Diarrhea, nausea, and vomiting may lead to dehydration which may cause kidney problems such as acute kidney injury and, in rare cases, requiring hemodialysis
A novel delayed-release preparation of metformin has recently been shown to improve glycaemic control to a similar extent to immediate-release metformin, but with less systemic exposure
Remarkably, several antidepressants, along with cocaine, act as inhibitors of NMTs without being transportable substrates themselves
Truemed itself does not make eligibility determinations
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