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Reduced vitamin E levels have been reported in studies on individuals affected by type 1 diabetes, and supplementation of vitamin E has been used to reduce oxidative stress [28]

In support of PKC overactivity in models of mental illness, a PRKCG KO mouse paradigm displays decreased anxiety ( 1.1 Signalling mechanisms across PKC Subfamilies Several PKC isoforms are associated with psychiatric illness, in particular, PRKCA and PRKCG have been the most studied in relation to psychopathology

To identify biological target-related signaling pathways associated with anti-AD, we used DAVID to identify enriched signaling pathways of 235 drug-disease intersection gene targets

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