allodynia with glp 1 If your skin hurts to touch while on GLP-1, you're not imagining it. A new case series documents as a dose-dependent side effect of GLP-1 medications. Here's what we know so far. Allodynia: Unusual Complication of GLP-1

Comparable to other peptides linked to fatty acids (e.g., the insulins detemir and degludec, the GLP-1RA liraglutide and semaglutide), the fatty acid side chain allows binding to albumin after subcutaneous injection, slows enzymatic degradation and prolongs biological half-life (5760)

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Yes, in narrower circumstances

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Government insurance (Medicaid, Medicare, and others) will generally cover GLP-1s and provide somewhat generous coverage (low out-of-pocket) if you can get it approved