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This review will discuss the contribution of integrins to the mechanisms regulating microtubule nucleation at the centrosome and microtubule stabilization at the cell cortex both during cell migration and the establishment of apicalbasal polarity, as well as the current understanding of how the assembly and turnover of integrin-mediated adhesions is regulated by changes in the microtubule cytoskeleton

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[1] [9] This is clinically important because medicines that inhibit CYP2C19 such as omeprazole, esomeprazole, and cimetidine can increase escitalopram plasma concentrations, potentially raising the risk of side effects including QT interval prolongation

Transfection HEK-293T cells were cultured in 100-mm dishes and transfected upon 70% confluency