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After the treatment period, rats were fasted overnight and anesthetized with pentobarbital (60 mg/kg, i.p.)

In liver from SF rats, glycine also decreases the insulin-induced phosphorylation of insulin receptor substrate-1 (ISR-1) in serine residue and increases the phosphorylation of insulin receptor -subunit (IR- ) in tyrosine residue

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GLP-1R surface expression and internalisation by confocal microscopy INS-1 832/3 GLP-1R KO cells were transiently transfected with SNAP/FLAG-hGLP-1R WT or cholesterol-binding mutants