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In studies using high doses of semaglutide 2.4 mg over 68 weeks, people lose on average 15-20% of their body weight

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Salamah HM, Marey A, ElSayed E, Hasan MT, Mahmoud A, Abualkhair KA, Abo-Elnour DE, Abdelhaleem IA, Abd-Elgawad M (2023) Efficacy and safety of polyethylene glycol loxenatide in type 2 diabetic patients: a systematic review and meta-analysis of randomized controlled trials