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In contrast to DRD2 in prolactinomas, the expression of FLNA in GH-secreting tumors did not correlate with SSTR2 levels, and FLNA silencing in human tumoral cells did not affect SSTR2 expression and membrane localization

As such, it appears that mitochondrial oxidative function and mt-DNA are required for energetically initiating the process of tumorigenesis, across multiple cancer types [3, 5]

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However, exclusive use of folic acid in treating vitamin B12 deficient megaloblastic anemia could result in progressive and irreversible neurologic damage