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The most common side effects with GLP-1 receptor agonists include: Nausea and vomiting Diarrhoea Pain in the stomach Constipation Indigestion Lack of appetite Low blood sugars Headaches Local skin reactions after injection However, symptoms usually taper off as therapy continues, especially for symptoms involving the digestive system

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It signals to the body to release another hormone, insulin, which helps move digested sugar from the blood into cells where it can be used for energy