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A variant here, P478L, is associated with SPCD 55 , and in human OCT1, the equivalent residues are also implicated in the inward-outward conformational transition 29

According to one analysis of clinical trials, L-carnitine may reduce weight by about 1.3 kg and decrease body mass index by about 0.5 kg/m2 compared to control in both nonobese and obese adults [28]

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