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Metabolic Adaptation and Plateauing: Why Weight Loss Slows Over Time After 6-12 months of GLP-1 use, some patients experience weight loss plateau as their body adapts to reduced caloric intake

But according to Dr Maran M, a gastro surgeon who regularly performs many appendix surgery in Chennai, it is not an easy sequence of events many times

Systemic inflammation is common in patients with type 2 diabetes

Nutritional Deficiencies Deficiencies in essential nutrients like Vitamin B12, Vitamin D, copper, iron, calcium, and zinc can lead to premature greying

For patients who are already experiencing significant nausea or who are at maximum tolerated dose, option 2 is safer