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Many individuals who have turned to GLP-1 (glucagon-like peptide-1) drugs for weight management find themselves wondering why these medicationsinitially effectiveseem to lose their potency over time

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In SURMOUNT-1, published in the New England Journal of Medicine, 57% of patients on 15 mg lost 20% or more of their body weight over 72 weeks, versus 3.1% loss in the placebo group

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