He's lost, like, four inches, so
4.2 Iron oxide Catalytic iron oxide nanoparticles (CAT-NPs) mimic natural peroxidases through their intrinsic catalytic activity
Unlike the human IgG1 constant region of L2-C, which might induce effector functions, the murine IgG1 constant region would not be expected to elicit effector function activity

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Here's the simple version: Your body stores fat in cells as fatty acids