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[ Acknowledgements We thank Sven Paul, Institute of Animal Breeding and Husbandry, University of Kiel, for revising the manuscript, Matthias Leippe, Department of Zoophysiology, University of Kiel, for helpful information and Virbac for providing the picture "Internal organs of the horse"

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FOXO4 is localized within the promyelocytic leukemia body in senescent cells and interacts with p53, inhibiting its nuclear exclusion 34

Retatrutide typically continues without cycling throughout weight loss and maintenance phases

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