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10.1038/s41388-024-03057-6 148 ZhouG.MengS.LiY.GhebreY

Day 1: 500mg NAD IV (1.5-3hrs) Day 4: 100mg NAD SQ Day 6: 100mg NAD SQ Daily: 250mg NR/NMN in the morning Week 7 We round off our loading phase with a large IV dose of NAD+, getting your body to optimal levels that we maintain throughout the rest of the cycle

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Yagi et al (84) demonstrated that GCG promoted the proliferation of HT29, SW480, CT26 and CMT93 cells through GCGR-dependent AMPK deactivation and MAPK activation, using 1.0 nM GCG replenished every 24 h for up to 72 h