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Then, 50 g of protein sample (Vprotein = 50/Cprotein/0.8) and 5 L of protein marker were added to the lanes

Intermediate Days: Comfort medications continue and are adjusted to manage withdrawal

[200] [199] Depending on the protein kinase involved and the residue(s) phosphorylated, phosphorylation can shift transporter function into an efflux-permissive state that causes the reverse transport of cytosolic monoamines into the synaptic cleft, or it can promote transporter internalization, whereby phosphorylated transporters are withdrawn from the plasma membrane and lower total reuptake capacity (i.e., non-competitive reuptake inhibition)