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Therefore, we need to explore the resistance mechanism of sorafenib and novel treatments against HCC, such as c-Met and downstream signaling pathway inhibitors (Hu et al., 2017)

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Preclinical studies using animal models or neuronal cell cultures for conditions such as Parkinson's or Alzheimer's disease often measure tissue-specific GSH levels and the GSH/GSSG ratio as key biomarkers of oxidative damage

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