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Lower GI pressure plays an important role in the pathogenesis of GERD

In studies, 4% to 8% of patients stopped treatment due to side effects such as nausea, vomiting, and/or diarrhea

In other words, if a pharmaceutical company thinks it can make a prescription drug out of a popular supplement ingredient, it can file a new drug application for a patented form of that ingredient, and the FDA will put out a letter stating that further sales of that ingredient in supplement form are prohibited

This effect could be attenuated by pre-surgery exposure to sucrose [77]

At the end of the trial, there were no significant weight loss differences between the groups