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Frandsens clinical approach integrates functional laboratory assessment, toxin-binding strategies, immune modulation, mitochondrial support, and individualized detoxification protocols

Importantly, there were no cardiovascular adverse events, no clinically significant changes in blood pressure or heart rate, no alterations in thyroid function, no immunogenicity with no anti-AOD-9604 antibodies detected, and no signs of tolerance or receptor desensitization

Can B12 Supplements Help a Sick Dog

These findings suggest that the observed trend toward benefit is unlikely to be driven by a single biased study, although the overall certainty of evidence remains limited by imprecision and heterogeneity

BMJ Nutr Prev Health