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doi: 10.3389/fphar.2019.00204 187 PerryV

Effects of Exendin-4 on Glucose Tolerance, Insulin Secretion, and Beta-Cell Proliferation Depend on Treatment Dose, Treatment Duration and Meal Contents

Three human serum samples were assayed 20 times in duplicate by three operators to determine precision between assays

13 Two meta-analyses of other GLP-1 RA CVOTs found that GLP-1 RAs were associated with greater rates of DR progression, but both studies found that the effect was driven by the extent of hemoglobin A1c reduction, rather than the medications themselves