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Health implications of high dietary omega-6 polyunsaturated Fatty acids

No significant alterations to mitochondrial mass were demonstrated following metformin treatment in HCT116 cells, however, in SW837 cells, mitochondrial mass was significantly increased following 24 h treatment with metformin (10 mM), when compared to control ( Figure 1C )

For comparison, vitamin C increased collagen in 50% of subjects, and retinoic acid (prescription-strength retinoid) increased collagen in only 40%

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