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Generally, the risk of B12 toxicity or overdose is only low, but keep in mind that vitamin B12 shots may probably give other side effects

Why Your B12 Shots Are Not Working Vitamin B12 and vitamin b12 shots have a long list of potential health improvement claims from low energy to neuropathy

J Ann Rheumatic Dis (2018) 77(Suppl 2):6034

Standard reconstitution for a 5mg vial: Add 2mL BAC water 2.5mg/mL (2,500mcg/mL) For a 300mcg dose: draw 12 units on an insulin syringe Store refrigerated after reconstitution

Immunol Rev 260(1):820 Petersson J, Schreiber O, Hansson GC, Gendler SJ, Velcich A, Lundberg JO et al (2011) Importance and regulation of the colonic mucus barrier in a mouse model of colitis