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At the end of the experiment, the weight of mice in the db/db + Reta group decreased, and at 10 weeks, db/db + Reta group mice had the lowest levels of body weight and food intake, followed by db/db + Tirz group and db/db + Lira group, with a statistically significant difference

Data shows a startling increase in the number of adults (aged 25 and older) and children and adolescents (aged five-24 years) who are overweight and obese worldwide, rising from 731 million and 198 million, respectively, in 1990, to 2.11 billion and 493 million in 2021

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