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Curcumins inhibition of COX-2 is noteworthy due to its non-selective and non-competitive nature, distinguishing it from specific nonsteroidal anti-inflammatory drugs (NSAIDs)

2.3.3 Nrf2/ARE-GPX4 pathway Current research suggests that Kelch-like ECH-associated protein 1 (Keap1) inhibits the activity of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2), which is a key regulator of oxidative stress

We found that Ac-DEVD-CHO, a caspase 3 inhibitor, better rescued cytotoxicity of NSBSO against B16 cells when comparing with the caspase 1 inhibitor (Z-YVAD-FMK) (Additional file 1: Fig

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I n seiner oxidierten Form kann Glutathion seine Aufgaben nicht mehr erfllen