Restless leg syndrome (RLS), also known as Willis-Ekbom disease, is a neurological sensorimotor disorder characterized by an overwhelming urge to move the legs, typically accompanied by uncomfortable sensations
Fluctuations in blood glucose can lead to feelings of fatigue, which, when coupled with irritability, may enhance the perception of aches and pains
So it may increase some risk if people are going to go to sources outside of the U.S
However, in a large study involving people with diabetes who had no comorbidities, GLP-1 RAs were not shown to increase the risk of developing pancreatitis at any time point up through 5 years of use.[ref][ref][ref][ref] The Cleveland Clinic now counsels that GLP-1 RA patients should be screened for pancreatitis risk factors, and a lower dose should be used to reduce the risk of pancreatitis.[ref] Related article : Pancreatitis and Genetic Risk Factors Gastroparesis: Case reports tie semaglutide to a risk of gastroparesis (very slow stomach emptying)
Journal of diabetes research
