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In some medications, especially those with a narrow therapeutic index, a dietary factor or supplement may be enough to move a patient from therapeutic benefit to drug toxicity

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for several indications: type 2 diabetes management (under the brand names Ozempic and Rybelsus), chronic weight management in adults with obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity (under the brand name Wegovy), and in adolescents aged 12 years and older with obesity

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The FDA-approved schedule increases doses every four weeks, starting from 2.5 mg to maintenance doses of 5 mg, 10 mg, or 15 mg weekly