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In drug-induced liver injury (DILI), the microbiota affects immune responses and drug metabolism by altering the bioavailability and toxicity of drugs through various biotransformation processes such as hydrolysis, demethylation, and oxidation.[57]

Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend

O (Outcome): Primary outcome: changes in serum Vitamin B12 levels, clinical improvement of Vitamin B12 deficiency symptoms

Pyruvate carboxylase (PC) is also a multifunctional enzyme containing all three activities in a single polypeptide that form an 4 homotetrameric enzyme

It can reduce blemishes and improve overall skin texture