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In A-induced AD model mice and APP23/PS45 double transgenic AD model mice, UA treatment promotes A clearance and improves cognitive deficits by restoring TFEB-dependent autophagy [217](Fig

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In animal studies, very high doses of sermorelin (several times the human dose) produced minor variations in fetal development in rats and rabbits

[PubMed] [Google Scholar] 42.Hemati K., Amini Kadijani A., Sayehmiri F., et al