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4 However, a 6-month placebo-controlled RCT in 54 non-smoking adults documented dose-dependent increases: at 1,000 mg/day, GSH levels rose 30-35% in erythrocytes, plasma, and lymphocytes, and 260% in buccal mucosal cells, with effects reversing after supplementation was stopped

For sudden flare-ups: Your doctor may advise temporarily increasing the dose

It is for this reason that B12 injections are sometimes used to offset the symptoms of having a B12 vitamin deficiency such as fatigue and weakness, poor moods, and low concentration

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d p-value based on analysis of covariance (ANCOVA) (comparison of data between the groups post-intervention, adjusted for baseline values, changes in physical activity, and energy intake)