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Expanding chemical biology of 2-oxoglutarate oxygenases

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On the other hand, the build-up of APP in axons and at synapses could cause rapid local increases in A levels following the increased cleavage of APP by - and - secretase

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Anyway, the fact that IGF-I redistribute among extravascular IGFBPs after passing the endothelium is likely to affect the local tissue bioavailability even more