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It is important to reduce the side effects of the drugs, which include gastrointestinal issues, nausea and bloating, as well as the risk of weight rebound without sustainable lifestyle changes

Semaglutide weight loss Studies show semaglutide helps people lose 15-20% of their body weight over several months

Additionally, the Wegovy 7.2mg higher-dose injectable is now available as of 2026

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Although indirect comparisons suggest that SGLT2 inhibitors may offer greater protection against kidney function decline, direct head-to-head trials are lacking