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their paucity in PD may lead to less SCFA availability and a thinner protective mucus layer

The most common myelin disorder of the CNS is multiple sclerosis (MS), characterized by motor, sensory and cognitive impairments resulting from demyelinating lesions, considered to be initiated by transgression of immune constituents across blood-brain and cerebrospinal fluid (CSF) barriers

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doi: 10.1111/j.1365-2133.2010.10147.x 75