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Benefits: Softens and smoothes the skin, provides long-lasting hydration, and has antibacterial properties

10.1038/s41420-023-01606-8 53 LiY.MaM.WangX.LiJ.FangZ.LiJ.et al (2024)

25, 38, 39 The combination of BSO (200 M) and L-PAM (25 M) achieved very strong synergism (CIN 0.1) in RPMI-8226 ( TP53 , KRAS and EGFR mutations) and U266 ( TP53 -mutation) cell lines, 38, 40 and strong synergism (CIN 0.10.3) was seen in MM.1S ( TP53 -wt and t(14;16)), KMS-12-PE (t(11;14) (q13;q32)) and EJM ( TP53 -mutation)

Glucose tolerance was quantified as the AUC integrated from 0-120 min

Such properties are responsible for their potency against voltage-gated ion channels, G-protein-coupled receptors and neurotransmitter transporters, making them attractive leads for drug development 6