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Pernicious anemia is an autoimmune condition that happens when your immune system produces antibodies that attack cells in the mucosal lining of your stomach and nerve cells

Individual response varies considerably, with some participants experiencing meaningful fat loss while others showed minimal changes

A 2016 study published in Nature Medicine demonstrated that MOTS-c administration improved insulin sensitivity and reduced diet-induced obesity in mouse models, even when started after metabolic dysfunction was already established

These drugs should be started at low doses, and given adequate time to reach peak effectiveness